Metabolic Syndrome Increases Risk of Death in Breast Cancer Survivors

Written by Camilla Jessen

Jan.14 - 2025 3:10 PM CET

Health
Photo: Shutterstock.com
Photo: Shutterstock.com
Metabolic disturbances are linked to a higher risk of relapse and death in breast cancer survivors.

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A new study shows that breast cancer survivors with metabolic syndrome face a higher risk of recurrence and a shorter lifespan compared to those without the condition.

Metabolic syndrome is a group of health issues caused by lifestyle factors, including high blood pressure, high blood sugar, abdominal obesity, and abnormal cholesterol levels. Together, these increase the risk of heart disease, diabetes, and other serious illnesses.

The research, conducted by Aarhus University Hospital and Aarhus University, analyzed data from over 42,000 breast cancer survivors.

The findings were published in the Journal of Internal Medicine and highlight the importance of focusing on lifestyle in the care and follow-up of breast cancer patients.

According to the study, survivors with metabolic syndrome have a much higher risk of their cancer returning and a greater chance of dying from it compared to survivors without the condition.

Call for New Guidelines

“These findings suggest we need to start screening for and treating metabolic syndrome in breast cancer survivors,” said Sixten Harborg, a doctor at Aarhus University Hospital and PhD student at Aarhus University.

“By addressing factors like obesity, high blood sugar, and cholesterol problems, we can help improve survival and quality of life for these patients,” Harborg added.

The researchers recommend new clinical guidelines that include metabolic health checks and treatments like dietary changes, regular exercise, and medication when necessary.

“Future research should focus on finding effective ways to manage metabolic syndrome and include metabolic health in breast cancer treatment plans,” said Signe Borgquist, senior consultant at Aarhus University Hospital and professor at Aarhus University.

Lifestyle Changes Can Make a Difference

The study shows that simple lifestyle changes can have a big impact.

For example, losing weight and managing blood sugar can reduce the risk of metabolic syndrome and improve cancer outcomes.

By combining cancer treatment with strategies to address metabolic health, survivors can have better outcomes and a higher quality of life.

This article is based on information from Via Ritzau.