Common Painkiller Linked to Potential Risks for Older Adults

New research challenges the safety of acetaminophen, a popular pain reliever, especially for individuals aged 65 and older.

What the Study Revealed

Researchers analyzed data from over 180,000 acetaminophen users and found increased risks for conditions like peptic ulcers, kidney disease, and hypertension.

Increased Risk of GI Bleeding

The study linked long-term acetaminophen use with serious complications, such as gastrointestinal bleeding.

"Minimal Pain-Relief Effect"

“Given its minimal pain-relief effect, the use of paracetamol for long-term conditions such as osteoarthritis needs to be carefully considered,” said Professor Weiya Zhang.

Expert Concerns About Safety

Dr. Marc Siegel noted: “It is generally accepted doctrine that acetaminophen is not associated with GI bleeding or advancing kidney disease, but the thinking is starting to change on this front.”

How Acetaminophen Works

Dr. Siegel explained that acetaminophen may affect similar pathways as ibuprofen, potentially leading to gastrointestinal side effects.

Study Limitations

The study was observational and could not track over-the-counter purchases, which researchers acknowledged as a limitation.

Risks for Older Adults

Dr. Macie P. Smith explained that older adults often metabolize drugs differently, which can increase risks.

Serious Potential Complications

Conditions like hypertension, kidney disease, and gastrointestinal bleeding could escalate to strokes, dementia, or premature death.

Advice for Older Adults

Always consult your doctor before taking over-the-counter medications, as many contain acetaminophen,” said Dr. Smith.

The Role of Pharmacists

Dr. Smith recommends using one pharmacy to help pharmacists monitor potential interactions and provide safety advice.

Read the Labels

Always read the included information, and don’t hesitate to ask your doctor or pharmacist if you have questions,” said Dr. Smith.

Balancing Risks and Benefits

“Discuss the risks and benefits with your doctor, and make an informed decision,” urged Dr. Smith.

A Wake-Up Call About Familiar Medications

This research serves as a reminder that even familiar drugs should be used with caution, especially by older adults.

Take Action on Your Health

With guidance from healthcare professionals, you can take control of your medications and ensure a healthier future.